Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.36 |
| ▸ | WEE1 | P30291 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CCND1 | P24385 | 4/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793085 | 0.79 | KDM4E (0.47) | MMP2MMP3MMP9CHEK1WEE1 | |
| SCHEMBL11313101 | 0.75 | PPOX (0.37) | CHEK1PRKCACDK4CCND1CDK5 | |
| SCHEMBL11838515 | 0.72 | KMT2A (0.38) | MMP2MMP3MMP9PRKCAEGFR | |
| SCHEMBL6929455 | 0.69 | WEE1 (0.37) | CHEK1WEE1CDK4CCND1CDK5 | |
| SCHEMBL5271087 | 0.69 | CES1 (0.55) | MMP2MMP3MMP9MEN1MAPT | |
| SCHEMBL8205630 | 0.68 | CDK4 (0.40) | CHEK1WEE1PRKCACDK4CCND1 | |
| SCHEMBL29860692 | 0.68 | ICMT (0.39) | WEE1 | |
| SCHEMBL2292542 | 0.65 | TXNRD1 (0.50) | CHEK1PRKCAEGFRMEN1MAPT | |
| SCHEMBL19421041 | 0.65 | GABRA1 (0.42) | CHEK1WEE1CDK4CCND1GSK3B | |
| SCHEMBL23197979 | 0.64 | APOBEC3G (0.48) | MMP2MMP3MMP9MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195986-A | Method for preparing polyolefin by metal-catalyzed ring-opening metathesis polymerization | 南京先进生物材料与过程装备研究院有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114195986-A | Method for preparing polyolefin by metal-catalyzed ring-opening metathesis polymerization | 南京先进生物材料与过程装备研究院有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195987-A | Method for preparing narrow-distribution polyolefin by photocatalytic ring-opening metathesis polymerization | 南京先进生物材料与过程装备研究院有限公司 | 2022-03-18 | — | — | CN | disclosed |