Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327838 | 0.89 | KLKB1 (0.43) | ALDH1A1GFERKLKB1HPGDLMNA | |
| SCHEMBL11691203 | 0.88 | CA2 (0.39) | ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL11692443 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1GFERHPGDLMNA | |
| SCHEMBL11322407 | 0.84 | CNR2 (0.46) | MAOB | |
| SCHEMBL11695597 | 0.79 | MAOB (0.43) | MAOB | |
| SCHEMBL6436974 | 0.79 | KDM4E (0.39) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL11321424 | 0.78 | NAAA (0.39) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL28261515 | 0.78 | NAAA (0.39) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL11313121 | 0.77 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDPDK2 | |
| SCHEMBL11693841 | 0.75 | EGFR (0.43) | SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4012360-A | Bis-salicyloyl-dicarboxylic acid dihydrazides as stabilizers for polyolefines | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |