Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321424 | 0.99 | NAAA (0.39) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL28261515 | 0.99 | NAAA (0.39) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL11689088 | 0.92 | GAA (0.41) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL11692443 | 0.85 | ALDH1A1 (0.54) | KDM4EGAASMN1; SMN2CA1CA9 | |
| SCHEMBL28537325 | 0.85 | TSHR (0.41) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL20952418 | 0.84 | HDAC3 (0.40) | KDM4ETSHRHTTHPGDHSD17B10 | |
| SCHEMBL548547 | 0.81 | CA1 (0.47) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL28489221 | 0.81 | HDAC3 (0.39) | KDM4EGAASMN1; SMN2MPOHIF1A | |
| SCHEMBL11327838 | 0.80 | KLKB1 (0.43) | HIF1ATSHRNPC1HPGDALDH1A1 | |
| SCHEMBL11313124 | 0.79 | KDM4E (0.39) | KDM4ESMN1; SMN2TSHRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397427-B1 | THERMOPLASTIC RESINS IN CONTACT WITH METALS OR METAL SALTS STABILIZED BY BLENDS OF DITHIOCARBAMATES AND METAL DEACTIVATORS | CROMPTON CORP (US) | 2005-11-16 | — | — | EP | claimed |
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4012360-A | Bis-salicyloyl-dicarboxylic acid dihydrazides as stabilizers for polyolefines | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-4002680-A | Process for the manufacture of acylhydrazines | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |