Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317577 | 0.85 | ADRB1 (0.47) | ATML3MBTL1PDE3BPDE3AGAA | |
| SCHEMBL11067771 | 0.75 | PDE3B (0.41) | L3MBTL1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL11058886 | 0.74 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11069955 | 0.74 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11070251 | 0.74 | ADRB1 (0.44) | ATMSMN1; SMN2 | |
| SCHEMBL11071107 | 0.73 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL11062197 | 0.72 | CCR1 (0.35) | ALDH1A1CCR1KCNH2 | |
| SCHEMBL12090742 | 0.71 | CYP19A1 (0.48) | GAAALDH1A1MEN1KMT2ACCR1 | |
| SCHEMBL11062648 | 0.71 | PDE3B (0.57) | PDE3BPDE3ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11071895 | 0.71 | PDE3B (0.40) | PDE3BPDE3AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |