Mandelic Acid

Mandelic Acid

SCHEMBL1131369

CC(O)N(C)C.O=C(O)[C@H](O)c1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.72
MAPK1 P28482 1/20 0.72
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 1/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ALOX5 P09917 1/20 0.47
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
SRC P12931 2/20 0.45
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
KMT2A Q03164 1/20 0.44
AOC3 Q16853 1/20 0.44
GAA P10253 1/20 0.44
MTOR P42345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL8630179 0.85 LMNA (0.82) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL7279536 0.85 LMNA (0.90) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL165161 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL29777368 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL21647917 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL5313046 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL1050 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL255601 0.85 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL1832893 0.83 LMNA (0.78) LMNAMAPK1KDM4EALDH1A1HPGD
Mandelic Acid SCHEMBL1832891 0.83 LMNA (0.78) LMNAMAPK1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US claimed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP claimed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP disclosed
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed