Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509457 | 0.83 | ALDH1A1 (0.47) | ACHEPANK3RPS6KA5RPS6KA4ADRB1 | |
| SCHEMBL22576020 | 0.83 | PANK3 (0.47) | ACHEPANK3RPS6KA5RPS6KA4KMT2A | |
| SCHEMBL31008978 | 0.83 | PANK3 (0.47) | ACHEPANK3RPS6KA5RPS6KA4KMT2A | |
| SCHEMBL2088418 | 0.81 | ALDH1A1 (0.46) | ACHEPANK3RPS6KA5RPS6KA4KMT2A | |
| SCHEMBL15887424 | 0.80 | PANK3 (0.48) | ACHEPANK3RPS6KA5RPS6KA4KMT2A | |
| SCHEMBL1110254 | 0.79 | PIK3CA (0.54) | ACHEPANK3KMT2AALDH1A1CNR2 | |
| SCHEMBL5758330 | 0.79 | ADRB1 (0.59) | ACHEPANK3KMT2AADRB1ALDH1A1 | |
| SCHEMBL18533994 | 0.79 | PANK3 (0.47) | PANK3RPS6KA5RPS6KA4KMT2AADRB1 | |
| SCHEMBL4042112 | 0.79 | HTR3A (0.53) | ACHEPANK3 | |
| SCHEMBL29434914 | 0.79 | PIK3CA (0.54) | ACHEPANK3KMT2AALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256738-A | BACTERICIDES, PYRIMIDINYL, QUINAZOLINYL | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |