Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314652 | 0.88 | TSHR (0.51) | TSHRGAAHSD17B10KMT2ATP53 | |
| SCHEMBL4602039 | 0.87 | TSHR (0.52) | TSHRGAAHSD17B10KMT2AMRGPRX4 | |
| SCHEMBL4602938 | 0.87 | PTPN11 (0.56) | TSHRGAAHSD17B10KMT2AMRGPRX4 | |
| SCHEMBL20522075 | 0.87 | GAA (0.61) | TSHRGAAMRGPRX4TP53ALDH1A1 | |
| SCHEMBL3385153 | 0.86 | TSHR (0.50) | TSHRGAAKMT2ATP53ALDH1A1 | |
| SCHEMBL1546386 | 0.86 | TSHR (0.52) | TSHRGAAHSD17B10KMT2AMRGPRX4 | |
| SCHEMBL1505156 | 0.86 | GAA (0.57) | TSHRGAAKMT2AMRGPRX4TP53 | |
| SCHEMBL1153890 | 0.85 | GAA (0.60) | TSHRGAAKMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL11627993 | 0.85 | MEN1 (0.53) | TSHRGAAKMT2ATP53ALDH1A1 | |
| SCHEMBL9187673 | 0.85 | TSHR (0.50) | TSHRGAAHSD17B10KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630541-B2 | Compounds useful as inhibitors of ALCAT 1 | PERENNA PHARMACEUTICALS, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| CN-120136858-A | Compounds useful as ALCAT1 inhibitors | 中美博瑞纳制药有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-110709394-B | Compounds useful as ALCAT1 inhibitors | 中美博瑞纳制药有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-117986199-A | Synthesis method of mosapride citrate impurity | 珠海润都制药股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20220089582-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | PERENNA PHARMACEUTICALS, INC. | 2022-03-24 | — | — | US | disclosed |
| US-11208404-B2 | Compounds useful as inhibitors of ALCAT 1 | PERENNA PHARMACEUTICALS, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200109136-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | PERENNA PHARMACEUTICALS, INC. | 2020-04-09 | — | — | US | disclosed |
| EP-3601274-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | Perenna Pharmaceuticals, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| CN-110709394-A | Compounds useful as ALCAT1 inhibitors | 中美博瑞纳制药有限公司 | 2020-01-17 | — | — | CN | disclosed |
| WO-2018178304-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | PERENNA PHARMACEUTICALS, INC. (US) | 2018-10-04 | — | — | WO | disclosed |
| WO-2008121558-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-10-09 | — | — | WO | disclosed |
| US-20080242654-A1 | N-[(2Z)-3-butyl-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene]-5-chloro-N',2-dimethoxybenzenecarboximidamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080064700-A1 | Aryl triazines as LPAAT-beta inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBVIE INC. | 2008-03-06 | — | — | US | disclosed |
| WO-2007140385-A2 | THIAZOLE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |
| US-7291616-B2 | Aryl triazines as LPAAT-β inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2003-08-14 | — | — | US | disclosed |
| WO-2003037346-A1 | 6-PHENYL-N-PHENYL-(1,3,5) -TRIAZINE-2,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOPHPHOSPHATIDIC ACID ACYLTRANSFERASE BETA (LPAAT-BETA) INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF CANCER | CELL THERAPEUTICS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089582-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | ACAT1, ACAT2, SLC33A1 | TSHR 3322/4885GAA 53/4885HSD17B10 178/4885 |
| US-20080242654-A1 | N-[(2Z)-3-butyl-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene]-5-chloro-N',2-dimethoxybenzenecarboximidamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | CNR2, CNR1, TRPV1 | TSHR 217/4885GAA 4848/4885HSD17B10 3482/4885 |
| US-12630541-B2 | Compounds useful as inhibitors of ALCAT 1 | LCLAT1, LPCAT1, ACAT2 | TSHR 3727/4885GAA 263/4885HSD17B10 609/4885 |
| US-11208404-B2 | Compounds useful as inhibitors of ALCAT 1 | ACAT1, ACAT2, SLC33A1 | TSHR 3322/4885GAA 53/4885HSD17B10 178/4885 |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | LPCAT3, LPCAT1, PLAAT2 | TSHR 769/4885GAA 1093/4885HSD17B10 887/4885 |
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | TSHR 1728/4885GAA 2221/4885HSD17B10 854/4885 |
| US-20200109136-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ALCAT 1 | ACAT1, ACAT2, SLC33A1 | TSHR 3322/4885GAA 53/4885HSD17B10 178/4885 |
| US-20080064700-A1 | Aryl triazines as LPAAT-beta inhibitors and uses thereof | LPCAT3, LPCAT1, PLAAT2 | TSHR 1011/4885GAA 692/4885HSD17B10 797/4885 |
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, OPRL1 | TSHR 334/4885GAA 2192/4885HSD17B10 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.