Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588269 | 0.81 | HDAC6 (0.44) | ALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL11423451 | 0.77 | KMT2A (0.34) | KDM4EHTT | |
| SCHEMBL11587704 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL16312316 | 0.73 | CYP1A2 (0.35) | ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL9688697 | 0.72 | PPARG (0.35) | MAPK1 | |
| SCHEMBL13865681 | 0.70 | — | — | |
| SCHEMBL14112926 | 0.70 | — | — | |
| SCHEMBL11665488 | 0.69 | L3MBTL1 (0.36) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL10403884 | 0.68 | — | — | |
| SCHEMBL28692284 | 0.65 | LMNA (0.40) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258184-A | ANTIBIOTICS | MEIJI SEIKA KAISHA LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
| US-4113944-A | DECARBOXYLATION | MEIJI SEIKA KAISHA, LTD. (JP) | 1978-09-12 | — | — | US | disclosed |