Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131570 | 1.00 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 | |
| SCHEMBL20323029 | 1.00 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Iodide SCHEMBL18063119 | 0.98 | MAPT (0.40) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL338804 | 0.98 | MAPT (0.40) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL338803 | 0.98 | MAPT (0.40) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Iodide SCHEMBL18063120 | 0.98 | MAPT (0.40) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Perchlorate SCHEMBL5860332 | 0.94 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 | |
| SCHEMBL6308287 | 0.94 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 | |
| SCHEMBL6308285 | 0.94 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 | |
| Perchlorate SCHEMBL5860330 | 0.94 | MAPT (0.41) | MAPTRAB9ANPC1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9855202-B2 | Compositions for dyeing hair with cationic direct dyes | NOXELL CORPORATION (US) | 2018-01-02 | — | — | US | disclosed |
| US-9849072-B2 | Method of coloring hair with direct dye compounds | NOXELL CORPORATION (US) | 2017-12-26 | — | — | US | disclosed |
| EP-2235114-B1 | POLYMERIC HAIR DYES | BASF SE (DE) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016146813-A1 | CATIONIC DIRECT DYES | BASF SE (DE) | 2016-09-22 | — | — | WO | disclosed |
| US-20160271030-A1 | Compositions for Dyeing Hair with Cationic Direct Dyes | DEUTSCHE BANK TRUST COMPANY AMERICAS, AS COLLATERAL AGENT | 2016-09-22 | — | — | US | disclosed |
| US-8992633-B2 | Disulfide dyes | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8962140-B2 | Functionalized core-shell nanoparticles | BASF SE (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20140157529-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-06-12 | — | — | US | disclosed |
| EP-2053094-B1 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |
| US-8641783-B2 | Disulfide or thiol polymeric hair dyes | BASF SE (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-1647580-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1609456-A1 | Use of polycationic azo compounds for dyeing keratinous fibres | L'OREAL (FR) | 2005-12-28 | — | — | EP | disclosed |
| EP-1399117-A1 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2004-03-24 | — | — | EP | disclosed |
| EP-1377265-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |
| EP-1377264-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |
| EP-1377262-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002100368-A1 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002078659-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002078658-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002078660-A1 | DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE | L'OREAL (FR) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140157529-A1 | DISULFIDE DYES | KRT18, COL1A1, SULT1A1 | MAPT 1432/4885RAB9A 3890/4885NPC1 4274/4885 |
| US-20160271030-A1 | Compositions for Dyeing Hair with Cationic Direct Dyes | TYR, SHH, COX5B | MAPT 399/4885RAB9A 2176/4885NPC1 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.