Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27583639 | 0.97 | HPGD (0.50) | HPGDKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL10171783 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2L3MBTL1P2RX4 | |
| SCHEMBL21178006 | 0.79 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4164688 | 0.79 | ALDH1A1 (0.51) | HPGDKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL1584775 | 0.79 | ALDH1A1 (0.51) | HPGDKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4098207 | 0.79 | MEN1 (0.53) | HPGDKDM4EALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL28676104 | 0.78 | P2RX4 (0.50) | KDM4EALDH1A1SMN1; SMN2L3MBTL1P2RX4 | |
| SCHEMBL15978138 | 0.77 | FPR1 (0.51) | HPGDKDM4EALDH1A1SMN1; SMN2P2RX4 | |
| SCHEMBL3993882 | 0.75 | KDM4E (0.48) | HPGDKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7521745 | 0.75 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1SMN1; SMN2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248999-A | ANTITUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-02-03 | — | — | US | disclosed |