Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584897 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2SRC | |
| SCHEMBL4164688 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2SRC | |
| SCHEMBL4098207 | 0.80 | MEN1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| Hydrogen Sulfide SCHEMBL27583639 | 0.79 | HPGD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL11315740 | 0.79 | HPGD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL15978138 | 0.79 | FPR1 (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3993882 | 0.76 | KDM4E (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL7521745 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL27422649 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL5797007 | 0.76 | CFTR (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046920-A1 | NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY | BAYLOR COLLEGE OF MEDICINE (US) | 2011-04-21 | — | — | WO | disclosed |