Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674249 | 0.88 | KDM4E (0.38) | BACE1KDM4EEPHX2SCN4ANPBWR1 | |
| SCHEMBL5996027 | 0.81 | BACE1 (0.45) | BACE1KDM4EEPHX2SCN4ANPBWR1 | |
| SCHEMBL10953240 | 0.80 | AMY1A (0.35) | BACE1KDM4E | |
| SCHEMBL11667779 | 0.79 | LMNA (0.39) | BACE1KDM4EEPHX2SCN4ANPBWR1 | |
| SCHEMBL782083 | 0.78 | ALDH1A1 (0.37) | BACE1KDM4ENPBWR1DYRK1A | |
| SCHEMBL25074830 | 0.78 | NPC1 (0.40) | SCN4ADYRK1ACBFBDHODHSCN10A | |
| SCHEMBL11152262 | 0.76 | PTGS2 (0.36) | BACE1KDM4ENPBWR1DYRK1A | |
| SCHEMBL780542 | 0.76 | HTT (0.44) | BACE1KDM4EL3MBTL1 | |
| SCHEMBL9941194 | 0.76 | MEN1 (0.38) | KDM4EL3MBTL1 | |
| SCHEMBL11462819 | 0.73 | CD38 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289771-A | BACTERICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |
| US-4239760-A | Combating fungi and bacteria with 3-azolyl-benzo-1,2,4-triazines and 1-oxides thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |