SCHEMBL11316699

SCHEMBL11316699

Cc1cccc(CCNCCO)c1C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
MTNR1A P48039 1/20 0.36
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CD38 P28907 1/20 0.35
CHRM2 P08172 1/20 0.34
MAPK8 P45983 2/20 0.34
PDCD1 Q15116 2/20 0.33
CD274 Q9NZQ7 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CCNE2 O96020 1/20 0.33
CDK4 P11802 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5465664 0.77 PARP1 (0.41) ALDH1A1KDM4EHPGDCD38MAPK8
SCHEMBL9201570 0.77 CHRM2 (0.50) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL2857937 0.76 GABRA1 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL7843739 0.75 BID (0.49) KDM4E
SCHEMBL311565 0.71 PARP1 (0.46) ALDH1A1KDM4EHPGDTSHRL3MBTL1
O-Xylene SCHEMBL28092337 0.69 ALDH1A1 (0.58) ALDH1A1KDM4ESMN1; SMN2CHRM2PDCD1
SCHEMBL21243271 0.67 CHRM2 (0.59) CA12CA1CA2CA9CHRM2
SCHEMBL14278970 0.67 MPO (0.43) ALDH1A1SMN1; SMN2
SCHEMBL11254093 0.67 ALDH1A1 (0.46) ALDH1A1KDM4EMTNR1AHPGDSMN1; SMN2
SCHEMBL8062508 0.67 HTR2A (0.60) MTNR1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299982-A CORROSION RESISTANCE PETROLITE CORPORATION (US) 1981-11-10 US disclosed
US-4270001-A CORROSION RESISTANCE; ENHANCED OIL RECOVERY PETROLITE CORPORATION (US) 1981-05-26 US disclosed
US-4168292-A IN OIL WELLS PETROLITE CORPORATION (US) 1979-09-18 US disclosed
US-4163771-A Hydroxyalkylaminoalkylamides as corrosion inhibitors for metals in an aqueous brine environment PETROLITE CORPORATION (US) 1979-08-07 US disclosed
US-4146556-A PROTECT METALLIC EQUIPMENT USED IN SECONDARY OIL RECOVERY FROM CORROSION BY BRINES PETROLITE CORPORATION (US) 1979-03-27 US disclosed
US-4060553-A FROM AN UNSATURATED NITRILE AND AN ALKANOLAMINE PETROLITE CORPORATION (US) 1977-11-29 US disclosed