Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317714 | 1.00 | F2 (0.41) | F2F10HPNHGFACST14 | |
| SCHEMBL31748248 | 0.86 | ALDH1A1 (0.45) | REN | |
| SCHEMBL22817289 | 0.86 | CASP1 (0.40) | RENPLK1 | |
| SCHEMBL22817362 | 0.86 | CASP1 (0.40) | RENPLK1 | |
| SCHEMBL22817333 | 0.83 | CASP1 (0.39) | — | |
| SCHEMBL11320821 | 0.82 | OPRM1 (0.42) | F2CTSBREN | |
| SCHEMBL22875706 | 0.81 | CASP1 (0.37) | — | |
| SCHEMBL12045120 | 0.81 | REN (0.41) | REN | |
| SCHEMBL29881596 | 0.80 | BACE1 (0.46) | — | |
| SCHEMBL31748029 | 0.80 | NPY4R (0.38) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308181-A | INSULIN B-CHAIN ANALOGS AS STIMULANTS OF T-CELL PROLIFERATION, FOR IMMUNE SYSTEM DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |