Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704446 | 0.80 | KMT2A (0.46) | ALDH1A1MEN1POLBGAAKMT2A | |
| SCHEMBL28482385 | 0.79 | CYP3A4 (0.46) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL12138180 | 0.79 | MEN1 (0.41) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL13473828 | 0.77 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL3472021 | 0.75 | CYP3A4 (0.58) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL30233139 | 0.75 | CYP3A4 (0.58) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL29975981 | 0.75 | CYP3A4 (0.58) | CYP3A4TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL18922735 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1TDP1POLBGAA | |
| SCHEMBL18361591 | 0.72 | LTA4H (0.47) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11312969 | 0.72 | CYP3A4 (0.54) | CYP3A4TSHRALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4163731-A | HYDRAULIC FLUIDS | CIBA-GEIGY AG (CH) | 1979-08-07 | — | — | US | disclosed |