Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922738 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL3723675 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL18067941 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL7704446 | 0.81 | KMT2A (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL25184625 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL3718510 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL17423549 | 0.76 | ALDH1A3 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL11825770 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL31397783 | 0.75 | PARP10 (0.38) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL10153872 | 0.74 | TDP1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669030-B2 | Hydantoin derivatives as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |