SCHEMBL11318137

SCHEMBL11318137

COc1ccc(C(=O)n2ncc3ccccc3c2=O)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
F12 P00748 3/20 0.52
HSD17B10 Q99714 3/20 0.52
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
MAPK1 P28482 1/20 0.52
KLK7 P49862 1/20 0.52
MAPK10 P53779 1/20 0.52
KLK5 Q9Y337 1/20 0.52
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
KLK3 P07288 5/20 0.48
MEN1 O00255 1/20 0.48
HSP90AB1 P08238 1/20 0.46
MAPT P10636 2/20 0.46
F2 P00734 2/20 0.46
BCHE P06276 2/20 0.45
ACHE P22303 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11322012 0.84 ELANE (0.54) KMT2AF12KDM4ENPC1RAB9A
SCHEMBL11311967 0.79 PLA2G10 (0.55) KMT2AHSD17B10KDM4ENPC1RAB9A
SCHEMBL4580147 0.72 PLA2G10 (0.50) KMT2AHSD17B10KDM4ENPC1RAB9A
SCHEMBL10977450 0.72 PLA2G10 (0.50) KMT2AHSD17B10KDM4ENPC1RAB9A
SCHEMBL27712242 0.72 F12 (0.59) KMT2AF12HSD17B10KDM4EUSP2
SCHEMBL29462183 0.71 TDP1 (0.44) KMT2AKDM4ENPC1RAB9AMEN1
SCHEMBL7365689 0.71 PLA2G10 (0.55) KMT2AHSD17B10KDM4ENPC1RAB9A
SCHEMBL8602385 0.71 PDE4A (0.63) HSD17B10KDM4EUSP2MAPK1MAPT
SCHEMBL11310234 0.70 KDM4E (0.46) KMT2AHSD17B10KDM4EUSP2NPC1
SCHEMBL31199185 0.69 AKR1C3 (0.55) KMT2AKDM4EMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed