Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291777 | 0.82 | ESR1 (0.46) | ESR1PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL15535075 | 0.80 | PLA2G2A (0.51) | PLA2G2APLA2G5FFAR1HTTTHRA | |
| SCHEMBL10355851 | 0.80 | PLA2G2A (0.51) | PLA2G2APLA2G5FFAR1HTTTHRA | |
| SCHEMBL11803127 | 0.79 | TTR (0.48) | HTTTTRMEN1KMT2ALMNA | |
| SCHEMBL10355740 | 0.79 | AKR1C2 (0.51) | ESR1PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL11292052 | 0.78 | PLA2G2A (0.49) | PLA2G2APLA2G5FFAR1HTTTHRA | |
| Hydrochloric Acid SCHEMBL11293609 | 0.77 | PLA2G2A (0.48) | PLA2G2APLA2G5FFAR1HTTTHRA | |
| SCHEMBL17804319 | 0.76 | L3MBTL1 (0.41) | TTRTDP1GPR35 | |
| SCHEMBL11298360 | 0.76 | HTT (0.48) | PLA2G2APLA2G5FFAR1HTTTHRB | |
| SCHEMBL31563703 | 0.75 | TTR (0.50) | HTTTTRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |