Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804346 | 0.87 | DHODH (0.44) | L3MBTL1FBP1HPGDALDH1A1TSHR | |
| SCHEMBL2080107 | 0.82 | ALDH1A1 (0.52) | L3MBTL1HPGDALDH1A1TSHRTDP1 | |
| SCHEMBL18830361 | 0.79 | GPR35 (0.46) | HPGDALDH1A1TSHRGPR35ALOX15 | |
| SCHEMBL9988172 | 0.78 | ALDH1A1 (0.52) | L3MBTL1HPGDALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL31413031 | 0.77 | GPR35 (0.47) | HPGDALDH1A1TSHRGPR35ALOX15 | |
| SCHEMBL1494608 | 0.77 | CYP3A4 (0.52) | FBP1HPGDALDH1A1TSHRGPR35 | |
| SCHEMBL7902277 | 0.77 | GPR35 (0.47) | HPGDALDH1A1TSHRGPR35ALOX15 | |
| SCHEMBL11271485 | 0.77 | VCAM1 (0.44) | L3MBTL1HPGDALDH1A1TSHRALOX15 | |
| SCHEMBL11318804 | 0.76 | ESR1 (0.48) | GPR35TDP1TTR | |
| SCHEMBL6121980 | 0.76 | ALDH1A1 (0.47) | HPGDALDH1A1TSHRGPR35ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |