Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669219 | 0.81 | GAA (0.46) | GAATDP1RXFP1MAPTTHRB | |
| SCHEMBL11281937 | 0.76 | TDP1 (0.47) | GAATDP1RXFP1MAPTTHRB | |
| SCHEMBL9135913 | 0.76 | GAA (0.45) | GAATDP1RXFP1MAPTTHRB | |
| SCHEMBL11283145 | 0.74 | MAPK14 (0.47) | GAARXFP1MAPTPYGLMEN1 | |
| SCHEMBL11273034 | 0.72 | SMN1; SMN2 (0.41) | GAARXFP1MAPTTHRBKDM4E | |
| SCHEMBL11276599 | 0.70 | TLR7 (0.43) | GAAMAPTKDM4EP2RX1P2RX4 | |
| SCHEMBL11295984 | 0.70 | GAA (0.47) | GAATDP1RXFP1MAPTTHRB | |
| SCHEMBL11286418 | 0.70 | RXFP1 (0.46) | GAATDP1RXFP1MAPTPYGL | |
| SCHEMBL7752690 | 0.69 | KDM4E (0.53) | GAATDP1RXFP1MAPTRORC | |
| SCHEMBL11281897 | 0.69 | RXFP1 (0.48) | GAATDP1RXFP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |