Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oxytetracycline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 10/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | USP2 | O75604 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 6/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.70 |
| ▸ | RECQL | P46063 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxytetracycline SCHEMBL124996 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL5489972 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL28245415 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL29365107 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL18918485 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL28562487 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL459700 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL9128434 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL13782519 | 0.99 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL2614977 | 0.99 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 12641 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079697-A | Seaweed oligopeptide fertilizer for rooting and strengthening seedlings and production process thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-120754262-B | Nucleic acid delivery vector and preparation method and application thereof | Shenzhen Jinlin Biotechnology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-117983265-B | Dendritic ternary SrCO3-TiO2Preparation method of/CdS composite structural material, prepared material and application | Huai'an University (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122006729-A | MOF-derived Sm doped Co3O4Method for preparing catalyst and application of catalyst in water treatment | 中国科学院地球化学研究所 | 2026-05-12 | — | — | CN | claimed |
| US-20260027140-A1 | COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA | ATOPIC MEDICAL INC (US) | 2026-01-29 | — | — | US | claimed |
| EP-3578542-B1 | COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-3578543-B1 | COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-08-20 | — | — | EP | claimed |
| CN-120195301-A | Method and system for detecting various antibiotics in water based on artificial intelligence | 广东中加检测技术股份有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-115557975-B | Cu-based mixed ligand photo-Fenton catalyst and preparation method and application thereof | 辽宁大学 | 2025-06-13 | — | — | CN | claimed |
| CN-118465149-B | Pretreatment method for improving analysis efficiency of various antibiotics in organic fertilizer | 生态环境部南京环境科学研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-1052775-A | A kind of preparation method of prawn young bait | YANG DONGHUI (CN) | 1991-07-10 | — | — | CN | claimed |
| CN-1012932-B | FEED FOR CARRIER PIGEON | ZHONGHUA INST OF CARRIER PIGEO (CN) | 1991-06-26 | — | — | CN | claimed |
| CN-1050975-A | Refined granular yeast fodder and preparation method | SHENXUE FODDER PROCESS FACTORY (CN) | 1991-05-01 | — | — | CN | claimed |
| CN-1049087-A | HIGH-EFFICIENT COMPOUND PRE-MIXING FEED ADDITIVE | FEED EXPERIMENT FACTORY JIANGX (CN) | 1991-02-13 | — | — | CN | claimed |
| CN-1048146-A | Growth promoter for hot pepper | RES INST OF VEGETABLES HUNAN A (CN) | 1991-01-02 | — | — | CN | claimed |
| EP-0372130-A1 | Coating medical devices with cationic antibiotics | C.R. BARD, INC. (US) | 1990-06-13 | — | — | EP | claimed |
| CN-1038748-A | FEED FOR CARRIER PIGEON | PENG CHENG (CN) | 1990-01-17 | — | — | CN | claimed |
| CN-1037442-A | FODDER CONCENTRATE CONTAINING HIGH PROTEIN CONTENT | XU CHUANDE (CN) | 1989-11-29 | — | — | CN | claimed |
| CN-86108557-A | With proteinaceous waste material is material, enzyme method method of extracting protein hydrolystate and products thereof | — | 1988-07-13 | — | — | CN | claimed |
| CN-86105108-A | Feed stuff for pet fish | — | 1988-03-02 | — | — | CN | claimed |