Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oxytetracycline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 10/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | USP2 | O75604 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 6/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.70 |
| ▸ | RECQL | P46063 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxytetracycline SCHEMBL5489972 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL28245415 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL29365107 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL113193 | 1.00 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL18918485 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL28562487 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL459700 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL9128434 | 0.99 | TDP1 (0.69) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL13782519 | 0.99 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT | |
| Oxytetracycline SCHEMBL2614977 | 0.99 | TDP1 (0.70) | TDP1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4557 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071006-A | Urea modified Bi2O3/g-C3N4Heterojunction catalyst and preparation method and application thereof | 武汉纺织大学 | 2026-05-22 | — | — | CN | claimed |
| US-20260076364-A1 | NON-AQUEOUS SOLUTION OF AGRICULTURAL ANTIBIOTICS | SHETH RITESH B (US) | 2026-03-19 | — | — | US | claimed |
| US-20250374923-A1 | CONTROLLING CITRUS GREENING IN CITRUS PLANTS USING OXYTETRACYCLINE | INVAIO SCIENCES INC (US) | 2025-12-11 | — | — | US | claimed |
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| US-20250312046-A1 | LIGATION CLIP AND PREPARATION METHOD THEREOF | SICHUAN GUONA TECHNOLOGY CO., LTD. (CN) | 2025-10-09 | — | — | US | claimed |
| EP-4628110-A1 | LIGATING CLIP | Chengdu Guona Technology Co., Ltd (CN) | 2025-10-08 | — | — | EP | claimed |
| CN-120189726-A | Crystallization device of oxytetracycline hydrochloride and working method thereof | 盐城市大丰区天生联合药业有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120189977-A | Preparation method of biomass cellulose carbon aerogel loaded iron-copper bimetallic catalyst | 中国民航大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120132791-A | Application of biomass porous carbon in tetracycline drug wastewater treatment | 中国民航大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120115039-A | Mixing tank for oxytetracycline hydrochloride and working method thereof | 盐城市大丰区天生联合药业有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-0088943-B1 | COMPOSITION FOR THE RESORPTION OF INJECTED ANTIBACTERIAL SUBSTANCES AND MIXTURES CONTAINING A BENZYL AMINE DERIVATIVE | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-08-13 | — | — | EP | claimed |
| US-4579686-A | Process for the preparation of easy-flowing (flowable) oxytetracyclin hydrochloride | BIOGAL GYOGYSZERGYAR (HU) | 1986-04-01 | — | — | US | claimed |
| EP-0038013-B1 | INJECTABLE OXYTETRACYCLINE COMPOSITIONS | SDS BIOTECH CORPORATION (US) | 1985-07-10 | — | — | EP | claimed |
| EP-0122709-A1 | Improvements in or relating to antibiotic or germicide layered implants | ELI LILLY AND COMPANY (US) | 1984-10-24 | — | — | EP | claimed |
| US-4439198-A | Biodegradable ocular insert for controlled delivery of ophthalmic medication | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1984-03-27 | — | — | US | claimed |
| US-4399127-A | MAGNESIUM OXIDE, HYDROXIDE OR CARBONATE; A GLYCEROL FORMAL8 ANTIOXIDANT, BUFFER | DIAMOND SHAMROCK CORPORATION (US) | 1983-08-16 | — | — | US | claimed |
| US-4386083-A | STABLE, LOW VISCOSITY | FERMENTA ANIMAL HEALTH COMPANY | 1983-05-31 | — | — | US | claimed |
| EP-0038013-A2 | Injectable oxytetracycline compositions | SDS BIOTECH CORPORATION (US) | 1981-10-21 | — | — | EP | claimed |
| US-4024871-A | POLYURETHANE | ETHICON, INC. (US) | 1977-05-24 | — | — | US | claimed |
| US-3966808-A | HALOGENATION, DEHYDRATION, METHACYCLINE HYDROCHLORIDE | RACHELLE LABORATORIES ITALIA, S.P.A. (IT) | 1976-06-29 | — | — | US | claimed |