Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828913 | 1.00 | PTPN1 (0.60) | PTPN1CA2CA1ACEFPR2 | |
| SCHEMBL7824676 | 1.00 | PTPN1 (0.60) | PTPN1CA2CA1ACEFPR2 | |
| SCHEMBL7814592 | 0.90 | FPR2 (0.63) | PTPN1CA2ACEFPR2HCRTR2 | |
| SCHEMBL8412092 | 0.90 | FPR2 (0.63) | PTPN1CA2ACEFPR2HCRTR2 | |
| SCHEMBL10449482 | 0.90 | FPR2 (0.63) | PTPN1CA2ACEFPR2HCRTR2 | |
| SCHEMBL28299473 | 0.88 | CA2 (0.56) | PTPN1CA2CA1ACEFPR2 | |
| SCHEMBL11316966 | 0.85 | FOS (0.56) | CA2FPR2FOSTTRJUN | |
| SCHEMBL11316963 | 0.85 | FOS (0.56) | CA2FPR2FOSTTRJUN | |
| SCHEMBL10441905 | 0.84 | CA2 (0.73) | PTPN1CA2CA1ACEMME | |
| SCHEMBL8409216 | 0.84 | CA2 (0.73) | PTPN1CA2CA1ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969397-A | Process for the preparation of l-dopa | HOFFMANN-LA ROCHE INC. (US) | 1976-07-13 | — | — | US | claimed |
| US-20170266353-A1 | BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE | DSM IP ASSETS BV (NL) | 2017-09-21 | — | — | US | disclosed |
| EP-3142714-A1 | BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE | DSM IP Assets B.V. (NL) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015175665-A1 | BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE | DSM IP ASSETS B.V. (NL) | 2015-11-19 | — | — | WO | disclosed |
| US-4294989-A | OPTICALLY ACTIVE HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4265827-A | METHYLCYCOHEXYL-O-ANISYLARSINE OPTICALLY ACTIVE CATALYST | MONSANTO COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4261919-A | OF BETA-SUBSTITUTED-ALPHA-ACYLAMIDO-ACRYLIC ACIDS TO YIELD OPTICALLY ACTIVE MIXTURE | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4124533-A | HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-3969397-A | Process for the preparation of l-dopa | HOFFMANN-LA ROCHE INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969397-A | Process for the preparation of l-dopa | HOFFMANN-LA ROCHE INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3714242-A | PROCESS FOR THE PREPARATION OF L-DOPA | HOFFMANN LA ROCHE | 1973-01-30 | — | — | US | disclosed |