Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322274 | 0.90 | ALOX5 (0.44) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11333367 | 0.86 | ALOX5 (0.46) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11326306 | 0.86 | CCKBR (0.41) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11320266 | 0.84 | POLB (0.45) | SMN1; SMN2MAPTL3MBTL1OPRD1OPRM1 | |
| SCHEMBL11314446 | 0.82 | TSHR (0.51) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11313090 | 0.82 | ALOX5 (0.51) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11315773 | 0.82 | ALOX5 (0.51) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11317245 | 0.81 | PTGIR (0.42) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11224743 | 0.81 | POLB (0.40) | CYP3A4CYP2D6SMN1; SMN2OPRD1OPRM1 | |
| SCHEMBL11226461 | 0.78 | CYP3A4 (0.47) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |