Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320450 | 0.86 | ALOX5 (0.45) | ALOX5TP53CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11312650 | 0.86 | KIF11 (0.41) | KIF11LTA4HCHRM1SMN1; SMN2MEN1 | |
| SCHEMBL11322274 | 0.85 | ALOX5 (0.44) | ALOX5TP53CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11326306 | 0.81 | CCKBR (0.41) | ALOX5CYP3A4CYP2D6CYP2C19CXCR3 | |
| SCHEMBL11236425 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL6228360 | 0.73 | ALOX5 (0.52) | ALOX5TP53LTA4HSMN1; SMN2MEN1 | |
| SCHEMBL11328131 | 0.72 | SMN1; SMN2 (0.49) | ALOX5CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL11317245 | 0.71 | PTGIR (0.42) | ALOX5TP53CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11327056 | 0.71 | POLB (0.43) | SMN1; SMN2 | |
| SCHEMBL11320601 | 0.71 | CFTR (0.42) | ALOX5CYP3A4CXCR3HSP90AA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |