Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334172 | 0.83 | ALDH1A1 (0.55) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL11328386 | 0.81 | LMNA (0.49) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL11323993 | 0.80 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL11323762 | 0.78 | LMNA (0.46) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL2170205 | 0.78 | LMNA (0.56) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL12877013 | 0.75 | PTGS1 (0.54) | LMNAMAPTMEN1PKMMAPK1 | |
| SCHEMBL2172320 | 0.72 | LMNA (0.53) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL2609447 | 0.71 | LMNA (0.56) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL8971698 | 0.71 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPTGAA | |
| SCHEMBL5968543 | 0.69 | LMNA (0.57) | LMNAPDE10AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293702-A | FROM 2-ALKOXYBENZOTHIAZOLES; CATALYST OF TERTIARY AMINE, QUATERNARY AMMONIUM COMPOUND OR DIALKYL SULFATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-06 | — | — | US | disclosed |