Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170205 | 0.81 | LMNA (0.56) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL11320534 | 0.80 | LMNA (0.47) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL13860626 | 0.79 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTHPGDGAA | |
| SCHEMBL11334172 | 0.77 | ALDH1A1 (0.55) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL2172320 | 0.75 | LMNA (0.53) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL11328386 | 0.75 | LMNA (0.49) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL2609447 | 0.75 | LMNA (0.56) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL8971698 | 0.74 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL11323762 | 0.73 | LMNA (0.46) | LMNAPDE10AALDH1A1MAPTHPGD | |
| SCHEMBL11218369 | 0.73 | ALOX15 (0.47) | ALDH1A1MAPTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293702-A | FROM 2-ALKOXYBENZOTHIAZOLES; CATALYST OF TERTIARY AMINE, QUATERNARY AMMONIUM COMPOUND OR DIALKYL SULFATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-06 | — | — | US | disclosed |