SCHEMBL2170205

SCHEMBL2170205

COc1nc2c(Cl)cccc2s1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
PDE10A Q9Y233 1/20 0.56
F2RL3 Q96RI0 3/20 0.54
MAPT P10636 6/20 0.51
ALDH1A1 P00352 5/20 0.51
KMT2A Q03164 4/20 0.51
GAA P10253 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
MEN1 O00255 3/20 0.51
HPGD P15428 2/20 0.51
PKM P14618 2/20 0.51
MAPK1 P28482 1/20 0.51
PSMB8 P28062 1/20 0.51
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 1/20 0.44
NPC1 O15118 1/20 0.43
POLA1 P09884 1/20 0.42
KDM4E B2RXH2 3/20 0.41
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11334172 0.81 ALDH1A1 (0.55) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL11323993 0.81 LMNA (0.51) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL5730270 0.80 ALDH1A1 (0.67) LMNAF2RL3MAPTALDH1A1KMT2A
SCHEMBL11321647 0.80 ALDH1A1 (0.58) LMNAF2RL3MAPTALDH1A1KMT2A
SCHEMBL2172320 0.79 LMNA (0.53) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL11328386 0.79 LMNA (0.49) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL10814903 0.79 ALDH1A1 (0.44) F2RL3MAPTALDH1A1KMT2AGAA
SCHEMBL10336475 0.79 TDP1 (0.51) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL8971698 0.78 LMNA (0.51) LMNAPDE10AF2RL3MAPTALDH1A1
SCHEMBL11320534 0.78 LMNA (0.47) LMNAPDE10AF2RL3MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP disclosed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US disclosed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN disclosed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO disclosed
US-4292243-A 3\"-Phenyldispiro[1,3-dioxolane-2,4'-cyclohexane-1',1\"-(3\"H)-isobenzofuran] HOECHST ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1981-09-29 US disclosed
US-4290958-A Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1981-09-22 US disclosed
US-4288623-A 1-Aryl-4-amino-cyclohexan-1-ols HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1981-09-08 US disclosed
US-4263317-A Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1981-04-21 US disclosed