SCHEMBL1132176

SCHEMBL1132176

Oc1ccc(/C=N/Nc2ccccc2)c(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.71
▸ KMT2A Q03164 9/20 0.71
▸ GAA P10253 8/20 0.71
▸ MAPT P10636 8/20 0.71
▸ ALDH1A1 P00352 6/20 0.71
▸ KDM4E B2RXH2 5/20 0.71
▸ HTT P42858 4/20 0.71
▸ DDX3X O00571 1/20 0.70
▸ HPGD P15428 6/20 0.70
▸ GFER P55789 1/20 0.70
▸ NCOA1 Q15788 1/20 0.62
▸ NCOA3 Q9Y6Q9 1/20 0.62
▸ ALOX12 P18054 1/20 0.62
▸ NPC1 O15118 4/20 0.58
▸ L3MBTL1 Q9Y468 4/20 0.58
▸ RAB9A P51151 4/20 0.58
▸ TDP1 Q9NUW8 3/20 0.58
▸ POLB P06746 2/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ ALPL P05186 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602635 1.00 MEN1 (0.71) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL1132125 1.00 MEN1 (0.71) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL1132158 0.84 MAPT (0.63) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL1132737 0.84 MEN1 (0.63) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL1132128 0.84 MAPT (0.63) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL1132877 0.84 MEN1 (0.63) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL11913667 0.83 DDX3X (1.00) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL31638206 0.82 KMT2A (1.00) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL734791 0.82 KMT2A (1.00) MEN1KMT2AGAAMAPTALDH1A1
SCHEMBL734790 0.82 KMT2A (1.00) MEN1KMT2AGAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727838-B1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS BREWER SCIENCE INC (US) 2023-08-09 — — EP claimed
US-10968348-B2 Laser-releasable bonding materials for 3-D IC applications BREWER SCIENCE, INC. (US) 2021-04-06 — — US claimed
EP-3727838-A1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS Brewer Science, Inc. (US) 2020-10-28 — — EP claimed
US-20190194453-A1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS BREWER SCIENCE, INC. 2019-06-27 — — US claimed
US-9512066-B2 Enhancers of protein degradation MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2016-12-06 — — US claimed
US-20120282629-A1 Enhancers of Protein Degradation MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2012-11-08 — — US claimed
EP-2488485-A1 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2012-08-22 — — EP claimed
WO-2011020883-A9 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2012-07-12 — — WO claimed
WO-2011020883-A1 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2011-02-24 — — WO claimed
EP-3727838-B1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS BREWER SCIENCE INC (US) 2023-08-09 — — EP disclosed
US-10968348-B2 Laser-releasable bonding materials for 3-D IC applications BREWER SCIENCE, INC. (US) 2021-04-06 — — US disclosed
EP-3727838-A1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS Brewer Science, Inc. (US) 2020-10-28 — — EP disclosed
US-20190194453-A1 LASER-RELEASABLE BONDING MATERIALS FOR 3-D IC APPLICATIONS BREWER SCIENCE, INC. 2019-06-27 — — US disclosed
US-9512066-B2 Enhancers of protein degradation MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2016-12-06 — — US disclosed
US-20120282629-A1 Enhancers of Protein Degradation MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2012-11-08 — — US disclosed
EP-2488485-A1 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2012-08-22 — — EP disclosed
WO-2011020883-A9 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2012-07-12 — — WO disclosed
WO-2011020883-A1 ENHANCERS OF PROTEIN DEGRADATION Max-Delbrück-Centrum für Molekulare Medizin (DE) 2011-02-24 — — WO disclosed
EP-2287149-A1 Enhancers of protein degradation MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) 2011-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282629-A1 Enhancers of Protein Degradation HTT, HYPK, TFEB MEN1 3413/4885KMT2A 2000/4885GAA 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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