Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SPOP | O43791 | 5/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132036 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL8745854 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132808 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132191 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132035 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL2339862 | 0.90 | TDP1 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL5718275 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL5718272 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL10711332 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL7572026 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043973-A1 | SIDEROPHORE CEPHALOSPORIN CONJUGATES AND USES THEREOF | Nabriva Therapeutics GmbH (AT) | 2021-03-11 | — | — | WO | disclosed |
| EP-1340762-B1 | Cephalosporin synthesis | SANDOZ AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| US-20030191105-A1 | Antibacterial cephalosporins | NABRIVA THERAPEUTICS AG (AT) | 2003-10-09 | — | — | US | disclosed |
| EP-1340762-A1 | Cephalosporin synthesis | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-09-03 | — | — | EP | disclosed |
| EP-0757691-B1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GMBH (AT) | 2003-07-02 | — | — | EP | disclosed |
| US-6531465-B1 | 7-acylamino-3-(imino)methyl cephalosporins; 7-[[(5-Amino-1,2,4-thiadiazol-3-yl)-(Z)-(fluormethoxyimino)acetyl]amino]-3-[[(piperazinoiminomethyl)hydrazono]methyl]-3-cephem-4-carboxylic acid; imination of 3-methyl derivative; acylation at the 7-amino; 1-[hydrazino(methylimino)methyl]piperazine intermediate | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-03-11 | — | — | US | disclosed |
| EP-0824535-B1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GMBH (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1221446-A1 | Antibacterial cephalosporins | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2002-07-10 | — | — | EP | disclosed |
| US-6093813-A | Cephalosporin compounds | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-07-25 | — | — | US | disclosed |
| US-6063917-A | Cephalosporin synthesis | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-05-16 | — | — | US | disclosed |
| US-6034237-A | 3-imino-cephalosporins | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-03-07 | — | — | US | disclosed |
| EP-0824535-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1998-02-25 | — | — | EP | disclosed |
| EP-0757691-A1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-02-12 | — | — | EP | disclosed |
| WO-1996035692-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1996-11-14 | — | — | WO | disclosed |
| WO-1995029182-A1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1995-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191105-A1 | Antibacterial cephalosporins | MRPL21, CIAPIN1, CSDE1 | TDP1 3986/4885KDM4E 4294/4885HSD17B10 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.