Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SPOP | O43791 | 5/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132036 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132808 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132191 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132192 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL1132035 | 1.00 | TDP1 (0.55) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL2339862 | 0.90 | TDP1 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL5718275 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL5718272 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL10711332 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL7572026 | 0.89 | DRD2 (0.54) | TDP1KDM4EHSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757691-A1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029182-A1 | CEPHALOSPORIN SYNTHESIS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1995-11-02 | — | — | WO | disclosed |