Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315131 | 0.91 | THRA (0.38) | KDM4EGABRA1GABRB2ALDH1A1ADRA2A | |
| SCHEMBL11312169 | 0.91 | CNR2 (0.38) | KDM4EGABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL11311117 | 0.90 | THRA (0.40) | KDM4EALDH1A1ADRA2ALMNAMAPT | |
| SCHEMBL11312254 | 0.87 | GABRA1 (0.36) | KDM4EGABRA1GABRB2ALDH1A1HTR1A | |
| SCHEMBL28552223 | 0.85 | L3MBTL1 (0.37) | KDM4EGABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL11318260 | 0.84 | ADRA2C (0.39) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL11319727 | 0.82 | GABRA1 (0.37) | KDM4EGABRA1GABRB2ALDH1A1HTR1A | |
| SCHEMBL11323265 | 0.80 | KDM4E (0.40) | KDM4EGABRA1GABRB2ALDH1A1HTR1A | |
| SCHEMBL11312138 | 0.80 | ADRA2C (0.39) | KDM4EGABRA1GABRB2ALDH1A1HTR1A | |
| SCHEMBL28545745 | 0.78 | TSHR (0.40) | KDM4EALDH1A1ADRA2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257987-A | SYNERGISTIC ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-24 | — | — | US | disclosed |