Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510562 | 0.84 | ACACB (0.54) | ACACBCA1CA2NPC1MTNR1A | |
| SCHEMBL28302050 | 0.82 | ACACB (0.52) | ACACBGRIA4NPC1MTNR1AMTNR1B | |
| SCHEMBL4442263 | 0.82 | ACACB (0.52) | ACACBGRIA4NPC1MTNR1AMTNR1B | |
| SCHEMBL4760955 | 0.82 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL28303465 | 0.82 | ACACB (0.52) | ACACBGRIA4NPC1MTNR1AMTNR1B | |
| SCHEMBL8384245 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL2091303 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL8384291 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL9512709 | 0.79 | MTNR1A (0.67) | ACACBNPC1MTNR1AMTNR1BKMT2A | |
| SCHEMBL16130561 | 0.79 | ACACB (0.49) | ACACBNPC1MTNR1AMTNR1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025331-A1 | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-18 | — | — | EP | disclosed |