Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322693 | 0.84 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4442263 | 0.84 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28302050 | 0.84 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28303465 | 0.84 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4760955 | 0.84 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8384291 | 0.83 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8384245 | 0.83 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL2091303 | 0.83 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL17469083 | 0.81 | NPC1 (0.64) | KDM4EF13A1ESR1ESR2NPC1 | |
| SCHEMBL9512709 | 0.81 | MTNR1A (0.67) | ACACBNPC1MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| CN-1011780-B | PROCESS FOR PRODUCING PHENOXYACETIC ACID DERIVATIVES | TANABE SEIYAKU CO (JP) | 1991-02-27 | — | — | CN | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| CN-87105501-A | New phenoxyacetic acid derivative and preparation method thereof and contain its and form as the medicine of activeconstituents | — | 1988-02-17 | — | — | CN | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |