Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510562 | 0.84 | ACACB (0.54) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL4442263 | 0.82 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL11322693 | 0.82 | ACACB (0.52) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL8384291 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL8384245 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL2091303 | 0.81 | MTNR1A (0.60) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL9512709 | 0.79 | MTNR1A (0.67) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL16130561 | 0.79 | ACACB (0.49) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL28904956 | 0.77 | MTNR1A (0.55) | ACACBNPC1MTNR1AMTNR1BRAB9A | |
| SCHEMBL9765333 | 0.74 | ALDH1A1 (0.66) | ACACBMTNR1AMTNR1BRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996567-A2 | NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME | ABBOTT LABORATORIES (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007095601-A2 | NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME | ABBOTT LABORATORIES (US) | 2007-08-23 | — | — | WO | disclosed |