Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.67 |
| ▸ | ACACB | O00763 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581724 | 0.83 | AOC3 (0.63) | MTNR1AMTNR1BACACBSMN1; SMN2NPC1 | |
| SCHEMBL9513697 | 0.83 | ACACB (0.61) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 | |
| SCHEMBL981303 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1BACACBSMN1; SMN2TRPV1 | |
| SCHEMBL5804284 | 0.83 | MEN1 (0.50) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 | |
| SCHEMBL9765333 | 0.81 | ALDH1A1 (0.66) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 | |
| SCHEMBL9510562 | 0.81 | ACACB (0.54) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 | |
| SCHEMBL11322693 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 | |
| SCHEMBL4760955 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BACACBNPC1ALDH1A1 | |
| SCHEMBL4442263 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BACACBSMN1; SMN2NPC1 | |
| SCHEMBL5051934 | 0.79 | KMT2A (0.56) | MTNR1AMTNR1BACACBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0325245-A1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |