Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973508 | 0.85 | TSHR (0.40) | MAPTMEN1KMT2APKMLMNA | |
| SCHEMBL10973513 | 0.85 | TSHR (0.40) | MAPTMEN1KMT2APKMLMNA | |
| SCHEMBL3766308 | 0.84 | ADRB2 (0.71) | ADRB2MAPTMEN1KMT2APKM | |
| SCHEMBL3766310 | 0.84 | ADRB2 (0.71) | ADRB2MAPTMEN1KMT2APKM | |
| SCHEMBL10973680 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2APKMLMNA | |
| SCHEMBL14985546 | 0.73 | ADRB2 (0.65) | ADRB2MAPTMEN1KMT2ALMNA | |
| SCHEMBL14982733 | 0.72 | ADRB2 (0.75) | ADRB2MAPTMEN1KMT2ALMNA | |
| SCHEMBL1656944 | 0.71 | MEN1 (0.51) | ADRB2MAPTMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL11513903 | 0.71 | INSR (0.40) | ADRB2MAPTMEN1KMT2APKM | |
| SCHEMBL10977272 | 0.70 | ADRB2 (0.48) | ADRB2MAPTMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306016-A | HETEROCYCLIC CYANINE DYE-LIKE NUCLEATING AGENTS | EASTMAN KODAK COMPANY (US) | 1981-12-15 | — | — | US | disclosed |