Sugi Predict

Sugi Predict / Compounds / SCHEMBL177279

SCHEMBL177279

SCHEMBL177279

CC(C)Oc1ccccc1C=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ HPGD P15428 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ ADRA2A P08913 1/20 0.53
▸ ADRA2B P18089 1/20 0.53
▸ ADRA2C P18825 1/20 0.53
▸ LMNA P02545 4/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ GAA P10253 1/20 0.52
▸ CYP1A2 P05177 2/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ CYP2C19 P33261 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.49
▸ ACHE P22303 1/20 0.49
▸ SRC P12931 1/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ TDP1 Q9NUW8 2/20 0.48
▸ THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356802 0.87 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL11323988 0.86 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL6706103 0.84 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL28570178 0.84 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL28061827 0.84 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL9723273 0.84 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL13988354 0.83 AR (0.49) ALDH1A1SMN1; SMN2LMNAKMT2ACYP1A2
SCHEMBL1748658 0.82 SRC (0.45) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL5303935 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDHTTADRA2A
SCHEMBL12283962 0.81 ERN1 (0.43) ALDH1A1SMN1; SMN2HPGDHTTADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4587669-B2 — — 2010-11-24 — — JP claimed
JP-2005509662-A — — 2005-04-14 — — JP claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 — — EP claimed
US-20030124157-A1 Compositions containing aromatic aldehydes and their use in treatments ALLERGAN, INC. 2003-07-03 — — US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 — — WO claimed
EP-4707264-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio SE (DE) 2026-03-11 — — EP disclosed
EP-4122924-B1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2025-11-19 — — EP disclosed
US-20250326744-A1 PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORPORATION (JP) 2025-10-23 — — US disclosed
CN-119816484-A Novel piperazine derivative or salt thereof and pharmaceutical composition 富士胶片株式会社 2025-04-11 — — CN disclosed
US-20250099481-A1 BCL-2 INHIBITORS NEWAVE PHARMACEUTICAL INC. 2025-03-27 — — US disclosed
US-20240287060-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-08-29 — — US disclosed
US-12065450-B2 Compounds and the use thereof in metathesis reactions VERBIO SE (DE) 2024-08-20 — — US disclosed
US-3959474-A 2,6-Diamino-1,4-dihydropyridine-3,5-dicarboxylic acid esters used as coronary vessel dilators and anti-hypertensive agents BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 — — US disclosed
US-3957998-A ADMINISTERING BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 — — US disclosed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 — — US disclosed
US-3950336-A HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 — — US disclosed
US-3946028-A HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed
US-3946027-A HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed
US-3943140-A HYPOTENSIVE, VASODILATION BAYER AKTIENGESELLSCHAFT (DT) 1976-03-09 — — US disclosed
US-3932526-A Fluoroaliphaticsulfonyl substituted ethylenes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099481-A1 BCL-2 INHIBITORS BCL2, BCL2L1, BCL2L10 ALDH1A1 3478/4885SMN1; SMN2 2544/4885HPGD 3819/4885
US-20030124157-A1 Compositions containing aromatic aldehydes and their use in treatments TYR, ALDH2, AOX1 ALDH1A1 4/4885SMN1; SMN2 3078/4885HPGD 286/4885
US-12065450-B2 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR ALDH1A1 1286/4885SMN1; SMN2 4408/4885HPGD 570/4885
US-20240287060-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CSNK1A1, CSNK1D, CSNK2A1 ALDH1A1 2913/4885SMN1; SMN2 2030/4885HPGD 3785/4885
US-20250326744-A1 PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION ABCB11, ABCC1, SLC11A2 ALDH1A1 774/4885SMN1; SMN2 2951/4885HPGD 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.