Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340039 | 0.85 | L3MBTL1 (0.63) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL3930253 | 0.84 | HTR1A (0.59) | L3MBTL1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL2965106 | 0.82 | MTNR1A (0.61) | POLBALDH1A1 | |
| SCHEMBL4576444 | 0.81 | L3MBTL1 (0.66) | L3MBTL1POLBSMN1; SMN2GLAPPARD | |
| SCHEMBL3140786 | 0.81 | PPARD (0.55) | L3MBTL1PPARDHPGDTSHR | |
| SCHEMBL31155848 | 0.81 | PPARD (0.52) | L3MBTL1POLBPPARDTSHRTDP1 | |
| SCHEMBL10438855 | 0.80 | CYP4F2 (0.58) | SMN1; SMN2ALDH1A1HPGDTSHRTDP1 | |
| SCHEMBL31155854 | 0.79 | PPARD (0.54) | PPARD | |
| SCHEMBL3266929 | 0.79 | PPARD (0.54) | PPARD | |
| SCHEMBL4752622 | 0.79 | L3MBTL1 (0.63) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |