Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332342 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11374737 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL9533123 | 0.84 | MAPK1 (0.51) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11343047 | 0.84 | MAPK1 (0.45) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11565546 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11561139 | 0.81 | CYP19A1 (0.45) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11327157 | 0.80 | MGLL (0.48) | ALDH1A1TDP1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11483915 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL9823499 | 0.76 | OPRK1 (0.40) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL7340516 | 0.73 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000373-B1 | IMIDAZOLE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULANTS OR PLANT PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0000373-A1 | Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-24 | — | — | EP | disclosed |