Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325321 | 1.00 | SMPD2 (0.56) | SMPD2MTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL11325323 | 1.00 | SMPD2 (0.56) | SMPD2MTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL11316938 | 0.78 | NFE2L2 (0.47) | CYP1A2CYP2D6MAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL11311800 | 0.78 | MAPT (0.45) | HDAC8HDAC6GRIK1GRIK2LMNA | |
| SCHEMBL11311798 | 0.78 | MAPT (0.45) | HDAC8HDAC6GRIK1GRIK2LMNA | |
| SCHEMBL11316940 | 0.78 | NFE2L2 (0.47) | CYP1A2CYP2D6MAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL11316941 | 0.78 | NFE2L2 (0.47) | CYP1A2CYP2D6MAPTSMN1; SMN2CYP1B1 | |
| SCHEMBL11311793 | 0.78 | MAPT (0.45) | HDAC8HDAC6GRIK1GRIK2LMNA | |
| SCHEMBL28458521 | 0.78 | SMPD2 (0.51) | SMPD2MTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL1248273 | 0.77 | MTNR1A (0.50) | SMPD2MTNR1AMTNR1BHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | claimed |
| US-4267359-A | Novel carboxylic acid esters | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |