Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311373 | 0.86 | NPC1 (0.61) | MAPTFFAR2KDM4EPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL11318580 | 0.85 | NPC1 (0.60) | MAPTFFAR2KDM4EPOLBMEN1 | |
| SCHEMBL1358311 | 0.83 | KDM4E (0.67) | FFAR2KDM4EPOLBSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11320673 | 0.82 | FFAR2 (0.70) | MAPTFFAR2KDM4EPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL11318575 | 0.82 | KDM4E (0.67) | MAPTFFAR2KDM4EPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL1358374 | 0.82 | KDM4E (0.65) | FFAR2KDM4EPOLBSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11314938 | 0.80 | RAB9A (0.66) | KDM4EPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9618481 | 0.77 | SCN3A (0.60) | SCN3AMAPTKDM4EPOLBEPHX2 | |
| SCHEMBL11329655 | 0.77 | MEN1 (0.55) | MAPTKDM4EPOLBEPHX2MEN1 | |
| Trifluoromethylbenzene SCHEMBL10350569 | 0.75 | MEN1 (0.65) | POLBMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305949-A | ANTIINFLAMMATORY AGENTS AND IMMUNOREGULATORY AGENTS | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |
| EP-0005070-B1 | N-(2-THIAZOLYL)AMIDES AND THEIR USE AS ANTI-INFLAMMATORY AND IMMUNOREGULATORY AGENTS | PFIZER INC. (US) | 1981-12-09 | — | — | EP | disclosed |
| EP-0005070-A2 | N-(2-thiazolyl)amides and their use as anti-inflammatory and immunoregulatory agents | PFIZER INC. (US) | 1979-10-31 | — | — | EP | disclosed |