Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298676 | 0.76 | KDM4E (0.44) | GAA | |
| SCHEMBL31508307 | 0.71 | GAA (0.61) | GAASLC9A1 | |
| SCHEMBL3336996 | 0.71 | GAA (0.61) | GAASLC9A1 | |
| SCHEMBL10324009 | 0.70 | SIRT2 (0.51) | GAA | |
| SCHEMBL9710977 | 0.68 | ALDH1A1 (0.49) | GAAHTR4 | |
| SCHEMBL10324220 | 0.67 | KEAP1 (0.46) | GAASLC9A1 | |
| Hydrochloric Acid SCHEMBL10322678 | 0.66 | KEAP1 (0.44) | GAASLC9A1 | |
| SCHEMBL3545080 | 0.62 | GAA (0.45) | GAAHTR4SLC9A1 | |
| SCHEMBL23948545 | 0.61 | SLC9A1 (0.49) | GAASLC9A1 | |
| SCHEMBL3544203 | 0.61 | KEAP1 (0.46) | GAASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098065-A1 | PYRIDO PYRIMIDINES FOR USE AS DYRK1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-07-26 | — | — | WO | disclosed |