SCHEMBL11328906

SCHEMBL11328906

C=CCN(CC=C)c1cccc2c1C(=O)OC2=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 1/20 0.36
PABPC1 P11940 1/20 0.36
KMT2A Q03164 1/20 0.36
TYMS P04818 2/20 0.35
POLB P06746 2/20 0.34
UTS2R Q9UKP6 1/20 0.32
C5AR1 P21730 1/20 0.31
TOP2A P11388 1/20 0.31
ALDH1A1 P00352 3/20 0.30
MAPK1 P28482 2/20 0.30
TSHR P16473 1/20 0.30
NSD2 O96028 1/20 0.30
EGFR P00533 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728510 0.77 MEN1 (0.60) TDP1ALOX15MEN1PABPC1KMT2A
SCHEMBL11638685 0.75 MEN1 (0.40) TDP1ALOX15MEN1PABPC1KMT2A
SCHEMBL11712271 0.73 MEN1 (0.41) TDP1ALOX15MEN1PABPC1KMT2A
SCHEMBL1478996 0.73 MEN1 (0.48) TDP1ALOX15MEN1PABPC1KMT2A
Propane SCHEMBL11526260 0.73 ALDH1A1 (0.38) TDP1MEN1PABPC1KMT2APOLB
SCHEMBL11546526 0.72 TDP1 (0.35) TDP1ALOX15PABPC1TYMSALDH1A1
SCHEMBL1566522 0.72 MAPT (0.56) TDP1ALOX15MEN1PABPC1KMT2A
SCHEMBL461695 0.71 GABRA1 (0.50) TDP1ALOX15MEN1KMT2ATYMS
SCHEMBL1509802 0.69 MEN1 (0.36) TDP1ALOX15MEN1KMT2AUTS2R
SCHEMBL9450404 0.69 ALDH1A1 (0.37) MEN1KMT2APOLBC5AR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4306073-A ADHESION PROMOTERS FOR GLASS FIBERS CIBA-GEIGY CORPORATION (US) 1981-12-15 US disclosed
US-4261898-A ADHESION PROMOTERS, CURING AGENTS CIBA-GEIGY CORPORATION (US) 1981-04-14 US disclosed
US-4176124-A ADHESION PROMOTERS BETWEEN SOLIDS AND ORGANIC RESINS OR CURING AGENTS FOR EPOXIDE RESINS CIBA-GEIGY CORPORATION (US) 1979-11-27 US disclosed
US-4158662-A STORAGE STABLE MOLDING MATERIAL CIBA-GEIGY CORPORATION (US) 1979-06-19 US disclosed
US-4140703-A CURING AGENTS FOR POLYEPOXIDES CIBA-GEIGY CORPORATION (US) 1979-02-20 US disclosed
US-4127712-A Phthalic acid diesters or ester-amides substituted by alkenylamino groups CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed