SCHEMBL461695

SCHEMBL461695

C=CCc1cccc2c1C(=O)OC2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.50
GABRB2 P47870 1/20 0.50
AKR1B1 P15121 1/20 0.43
KDM4E B2RXH2 5/20 0.42
GAA P10253 3/20 0.42
ALOX15 P16050 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
HPGD P15428 2/20 0.42
CYP2C19 P33261 2/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
ELANE P08246 1/20 0.39
TOP2A P11388 1/20 0.38
TYMS P04818 1/20 0.38
HSD17B10 Q99714 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Dioxide SCHEMBL29024226 0.95 GABRA1 (0.46) GABRA1GABRB2AKR1B1KDM4EGAA
SCHEMBL28420989 0.82 ELANE (0.41) GABRA1GABRB2AKR1B1KDM4EGAA
SCHEMBL6510106 0.79 TDP1 (0.40) GABRA1GABRB2AKR1B1KDM4EGAA
SCHEMBL3872705 0.79 ALOX15 (0.48) GABRA1GABRB2ALOX15HPGDTDP1
SCHEMBL1826217 0.77 ALOX15 (0.46) GABRA1GABRB2ALOX15CYP2D6TDP1
SCHEMBL5824091 0.76 GABRA1 (0.58) GABRA1GABRB2AKR1B1KDM4EGAA
SCHEMBL4063781 0.76 ALOX15 (0.44) GABRA1GABRB2ALOX15CYP2D6TDP1
SCHEMBL31192520 0.76 ALOX15 (0.44) ALOX15TDP1TYMSMEN1KMT2A
SCHEMBL31192516 0.76 ALOX15 (0.44) ALOX15TDP1TYMSMEN1KMT2A
SCHEMBL31192517 0.76 ALOX15 (0.44) ALOX15TDP1TYMSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4781862-A Process for the preparation of anthraquinone MONTVALE PROCESS COMPANY, INC. (US) 1988-11-01 US claimed
US-12031096-B2 Reduced fouling of hydrocarbon oil BL TECHNOLOGIES, INC. (US) 2024-07-09 US disclosed
CN-114929817-B Coating containing branched polyester polyol as plasticizer 巴斯夫涂料有限公司 2024-01-05 CN disclosed
US-20240006948-A1 Corona Shielding Strip for a High-Voltage Rotating Electrical Machine SIEMENS AKTIENGESELLSCHAFT (DE) 2024-01-04 US disclosed
EP-4208882-A1 CORONA SHIELDING STRIP FOR A HIGH-VOLTAGE ROTATING ELECTRIC MACHINE, USE THEREOF, AND ELECTRIC MACHINE Siemens Aktiengesellschaft (DE) 2023-07-12 EP disclosed
CN-116368183-A Corona shielding tape for a rotary high-voltage motor, use thereof and motor 西门子股份公司 2023-06-30 CN disclosed
US-20210222076-A1 REDUCED FOULING OF HYDROCARBON OIL GENERAL ELECTRIC COMPANY 2021-07-22 US disclosed
US-11015135-B2 Reduced fouling of hydrocarbon oil BL TECHNOLOGIES, INC. (US) 2021-05-25 US disclosed
US-20190203131-A1 REDUCED FOULING OF HYDROCARBON OIL BL TECHNOLOGIES, INC. 2019-07-04 US disclosed
EP-3504300-A1 REDUCED FOULING OF HYDROCARBON OIL General Electric Company (US) 2019-07-03 EP disclosed
EP-1577347-A1 AMORPHOUS, WHOLLY AROMATIC POLYESTERAMIDE COMPOSITION Polyplastics Co., Ltd. (JP) 2005-09-21 EP disclosed
EP-1501895-A1 COMPOSITIONS COMPRISING ANIONIC FUNCTIONALIZED POLYORGANOSILOXANES FOR HYDROPHOBICALLY MODIFYING SURFACES AND ENHANCING DELIVERY OF ACTIVE AGENTS TO SURFACES TREATED THEREWITH THE PROCTER & GAMBLE COMPANY (US) 2005-02-02 EP disclosed
WO-2003095559-A1 COMPOSITIONS COMPRISING ANIONIC FUNCTIONALIZED POLYORGANOSILOXANES FOR HYDROPHOBICALLY MODIFYING SURFACES AND ENHANCING DELIVERY OF ACTIVE AGENTS TO SURFACES TREATED THEREWITH THE PROCTER & GAMBLE COMPANY (US) 2003-11-20 WO disclosed
US-20030211050-A1 Compositions comprising anionic functionalized polyorganosiloxanes for hydrophobically modifying surfaces and enhancing delivery of active agents to surfaces treated therewith THE PROCTER & GAMBLE COMPANY 2003-11-13 US disclosed
CN-1393447-A Process for purifying sym-phenyltetraformic acid dianhydride ZHANG GUORUI (CN) 2003-01-29 CN disclosed
US-6040009-A SOLVENTS, POLYESTER RESIN, STAR OLIGOMER AND CURING AGENTS MAZDA MOTOR CORPORATION (JP) 2000-03-21 US disclosed
US-5773511-A LOW TEMPERATURE CURING MAZDA MOTOR CORPORATION (JP) 1998-06-30 US disclosed
EP-0688841-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR CORPORATION (JP) 1995-12-27 EP disclosed
US-4117198-A CROSSLINKED OIL-MODIFIED ALKYD RESIN; ACRYLIC COPOLYMER FORMICA CORPORATION (US) 1978-09-26 US disclosed
US-4076666-A ALKYD RESIN, POLYALKYLETHER OF A POLYMETHYLOL MELAMINE, COPOLYMER OF A MALEIC ACID, ESTER OR ANHYDRIDE AND AN OLEFIN OR VINYL ETHER FORMICA CORPORATION (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211050-A1 Compositions comprising anionic functionalized polyorganosiloxanes for hydrophobically modifying surfaces and enhancing delivery of active agents to surfaces treated therewith PLOD3, CUTA, PLOD2 GABRA1 3355/4885GABRB2 4018/4885AKR1B1 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.