Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | GRPR | P30550 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316943 | 0.92 | OPRD1 (0.42) | OPRM1OPRD1OPRK1GRPRGRN | |
| SCHEMBL17925467 | 0.92 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| SCHEMBL1275443 | 0.92 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| SCHEMBL1674833 | 0.92 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| Water SCHEMBL1433025 | 0.91 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| Water SCHEMBL1433018 | 0.91 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| Water SCHEMBL28629638 | 0.91 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| Hydrochloric Acid SCHEMBL30196080 | 0.91 | OPRM1 (0.46) | OPRM1OPRD1OPRK1GRPRCTSB | |
| SCHEMBL11330871 | 0.90 | OPRM1 (0.40) | OPRM1OPRD1OPRK1GRPRCA2 | |
| Hippuric Acid SCHEMBL1838491 | 0.87 | OPRD1 (0.49) | OPRM1OPRD1OPRK1GRPRCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292404-A | Method for determining the activity of the angiotensin-converting enzyme | FUJIZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | claimed |
| US-4292404-A | Method for determining the activity of the angiotensin-converting enzyme | FUJIZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |