SCHEMBL1674833

SCHEMBL1674833

CC(C)CC(NC(=O)C(Cc1c[nH]cn1)NC(=O)CNC(=O)c1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.46
▸ OPRD1 P41143 2/20 0.46
▸ OPRK1 P41145 2/20 0.46
▸ GPR139 Q6DWJ6 1/20 0.44
▸ MME P08473 2/20 0.43
▸ CDYL2 Q8N8U2 2/20 0.43
▸ CTSB P07858 2/20 0.42
▸ CBX7 O95931 1/20 0.42
▸ CBX8 Q9HC52 1/20 0.42
▸ CTSL P07711 2/20 0.41
▸ CTSS P25774 1/20 0.41
▸ CTSK P43235 1/20 0.41
▸ GRPR P30550 1/20 0.41
▸ PSMB5 P28074 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275443 1.00 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
SCHEMBL17925467 1.00 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
Hydrochloric Acid SCHEMBL30196080 0.99 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
Water SCHEMBL28629638 0.99 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
Water SCHEMBL1433025 0.99 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
Water SCHEMBL1433018 0.99 OPRM1 (0.46) OPRM1OPRD1OPRK1GPR139MME
SCHEMBL316943 0.93 OPRD1 (0.42) OPRM1OPRD1OPRK1GRPR
Hippuric Acid SCHEMBL1838491 0.93 OPRD1 (0.49) OPRM1OPRD1OPRK1CDYL2CTSB
SCHEMBL11330795 0.92 OPRM1 (0.42) OPRM1OPRD1OPRK1MMECDYL2
SCHEMBL11330871 0.90 OPRM1 (0.40) OPRM1OPRD1OPRK1MMECDYL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110438074-A A kind of immunocyte recovery culture solution and preparation method thereof GUANGZHOU SHAAI BIOLOGICAL TECH CO LTD 2019-11-12 — — CN claimed
CN-107325147-A The screening technique of fulvoushair honeysuckle flower moderate resistance hypertensin conversion enzyme activity composition 滨州医学院 2017-11-07 — — CN claimed
CN-101696233-B Albumin angiotensin converting enzyme inhibition peptide and preparation method thereof JILIN UNIVERSITY (CN) 2012-02-01 — — CN claimed
US-20080171698-A1 Anti-hypertensive molecules and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH. 2008-07-17 — — US claimed
CN-101020714-A Earthworm protein with function of lowering blood pressure and its prepn process TANG SHENGJIAN (CN) 2007-08-22 — — CN claimed
US-20050032709-A1 Anti-hypertensive molecules and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2005-02-10 — — US claimed
WO-2004087743-A2 ANTI-HYPERTENSIVE PEPTIDE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-10-14 — — WO claimed
CN-121270657-B Blood protein accurate active peptide with functions of tonifying qi and blood, improving microcirculation and promoting vasodilation, and preparation method and application thereof XIAMEN YUANZHIDAO BIOTECH Co.,Ltd. (CN) 2026-05-26 — — CN disclosed
EP-4374709-A1 METHOD FOR PRODUCING BIOACTIVE PEPTIDES OBTAINED FROM WHEY USING ENZYMES OF PLANT ORIGIN Pontificia Universidad Católica de Chile (CL) 2024-05-29 — — EP disclosed
CN-117534727-B Preparation method and application of food-borne antihypertensive peptide 中国药科大学 2024-04-19 — — CN disclosed
CN-117343132-B ACE (angiotensin converting enzyme) inhibitory peptide derived from salmon skin and preparation method thereof 山东省农业科学院 2024-03-12 — — CN disclosed
CN-117534727-A Preparation method and application of food-borne antihypertensive peptide 中国药科大学 2024-02-09 — — CN disclosed
CN-117343132-A ACE (angiotensin converting enzyme) inhibitory peptide derived from salmon skin and preparation method thereof 山东省农业科学院 2024-01-05 — — CN disclosed
US-4256751-A HYPOTENSIVE AGENTS TANABE SEIYAKU CO., LTD. (JP) 1981-03-17 — — US disclosed
EP-0024309-A2 Triazolopyridazine derivatives, process and intermediates for their preparation and medicaments containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-03-04 — — EP disclosed
EP-0018549-A2 Tetrahydroisoquinoline compounds, process for preparing them and pharmaceutical compositions containing them Tanabe Seiyaku Co., Ltd. (JP) 1980-11-12 — — EP disclosed
US-4226775-A HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1980-10-07 — — US disclosed
EP-0012845-A1 Tetrahydroisoquinoline compounds, process for preparing same and pharmaceutical compositions containing them Tanabe Seiyaku Co., Ltd. (JP) 1980-07-09 — — EP disclosed
EP-0010347-A1 Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation AMERICAN CYANAMID COMPANY (US) 1980-04-30 — — EP disclosed
US-3947575-A Peptides as argiotensin converting enzyme inhibitors E. R. SQUIBB & SONS, INC. (US) 1976-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171698-A1 Anti-hypertensive molecules and process for preparation thereof REN, ACE, AGT OPRM1 3426/4885OPRD1 3578/4885OPRK1 1440/4885
US-20050032709-A1 Anti-hypertensive molecules and process for preparation thereof AGT, ACE, REN OPRM1 2972/4885OPRD1 2814/4885OPRK1 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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