Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004573 | 0.86 | ALDH1A1 (0.62) | HTR2AHTR2CSLC6A4ALDH1A1MAPT | |
| SCHEMBL11289198 | 0.85 | MAPT (0.59) | HTR2AHTR2CSLC6A4ALDH1A1MAPT | |
| SCHEMBL11282901 | 0.84 | ALDH1A1 (0.56) | HTR2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL10763370 | 0.82 | HTR7 (0.61) | HTR2AHTR2CSLC6A4ALDH1A1DRD3 | |
| Hydrochloric Acid SCHEMBL11275337 | 0.82 | LMNA (0.52) | HTR2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL11284949 | 0.81 | POLB (0.59) | HTR2AHTR2CALDH1A1MAPTKDM4E | |
| SCHEMBL10762915 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL2111769 | 0.79 | SIGMAR1 (0.67) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL11199556 | 0.78 | ALDH1A1 (0.56) | HTR2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL11278842 | 0.78 | SIGMAR1 (0.62) | ALDH1A1MAPTKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048044-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | claimed |