Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569473 | 0.97 | SLC18A3 (0.46) | SLC18A3AGERSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11332126 | 0.90 | SLC18A3 (0.50) | SLC18A3AGERSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11456844 | 0.86 | SLC18A3 (0.48) | SLC18A3SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11332175 | 0.85 | SIGMAR1 (0.42) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11330691 | 0.84 | SIGMAR1 (0.38) | SLC18A3SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11330981 | 0.83 | SLC18A3 (0.45) | SLC18A3SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11338205 | 0.83 | MITF (0.53) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11346088 | 0.83 | SIGMAR1 (0.37) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11346481 | 0.82 | SIGMAR1 (0.36) | SLC18A3SMN1; SMN2MEN1KMT2AKDM4E | |
| Ethylbenzene SCHEMBL11337300 | 0.82 | AGER (0.40) | AGERSMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | claimed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | claimed |
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |