SCHEMBL11333385

SCHEMBL11333385

Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1S(=O)(=O)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 5/20 0.39
TSHR P16473 4/20 0.39
GPR35 Q9HC97 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HIF1A Q16665 1/20 0.38
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL11323603 0.86 TSHR (0.38) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL11321822 0.86 VCAM1 (0.44) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL11323613 0.84 GPR35 (0.44) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL30350503 0.79 TSHR (0.52) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL11435748 0.79 TSHR (0.52) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL8649537 0.78 CYP1A2 (0.52) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL11333391 0.77 TSHR (0.39) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL11755785 0.77 TSHR (0.49) VCAM1TSHRGPR35ALDH1A1TDP1
SCHEMBL3814710 0.77 KIF18A (0.39) VCAM1TSHRALDH1A1TDP1CYP1A2
SCHEMBL3646610 0.75 GPR35 (0.48) TSHRGPR35ALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297127-A PREEMERGENCE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
US-4251264-A 4-CYANO SUBSTITUTED AMERICAN CYANAMID COMPANY (US) 1981-02-17 US disclosed
US-4166908-A SELECTIVE PREEMERGENT ACTIVITY AMERICAN CYANAMID COMPANY (US) 1979-09-04 US disclosed
US-4165231-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1979-08-21 US disclosed
US-4025538-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1977-05-24 US disclosed